OUR SOLUTION
The Future is EpiSmart
The culmination of 10+ years of ophthalmology practice and research
EpiSmart™
EpiSmart™ Epithelium-On Cross-Linking System is a drug-device combination designed to treat keratoconus, a progressive corneal disease that can cause vision loss and blindness. The system combines our proprietary drug delivery devices, fixed-dose combination drug, and a patented UVA light device.
EpiSmart is designed to treat keratoconus across a wide spectrum of disease severity, including on diagnosis, through simultaneous bilateral, minimally-invasive treatment, allowing for rapid return to daily activities.*
EpiPrep™
EpiPrep disposable wand enhances epithelial permeability without disruption
EpiPrep disposable loading sponge maintains drug concentration during stromal loading
RiboStat™
High concentration of riboflavin drives diffusion into stroma
Ideal tonicity and pH facilitate penetration through intact epithelium
Sodium iodide removes peroxide, protects cornea and riboflavin, and catalyzes the most favorable reactions for efficient cross-linking
UVA Device
UV-A light activates riboflavin, which generates singlet oxygen for collagen cross-linking reaction
Dual-head design enables treatment of both eyes at the same time
* EpiSmart is an investigational drug-device combination product. EpiSmart and its components (Epiprep, Ribostat, and UVA Device) are not yet approved by the Food and Drug administration or by other regulatory bodies.